Immunohistochemical Study to Demonstrate Sarcocystis Neurona in Equine Protozoal Myeloencephalitis

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منابع مشابه

A review of Sarcocystis neurona and equine protozoal myeloencephalitis (EPM).

Equine protozoal myeloencephalitis (EPM) is a serious neurological disease of horses in the Americas. The protozoan most commonly associated with EPM is Sarcocystis neurona. The complete life cycle of S. neurona is unknown, including its natural intermediate host that harbors its sarcocyst. Opossums (Didelphis virginiana, Didelphis albiventris) are its definitive hosts. Horses are considered it...

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Previous challenge studies performed at Ohio State University involved a transport-stress model where the study animals were dosed with Sarcocystis neurona sporocysts on the day of arrival. This study was to test a second transportation of horses after oral inoculation with S. neurona sporocysts. Horses were assigned randomly to groups: group 1, transported 4 days after inoculation (DAI); group...

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Equine protozoal myeloencephalitis.

Equine protozoal myeloencephalitis (EPM) can be caused by either of 2 related protozoan parasites, Sarcocystis neurona and Neospora hughesi, although S. neurona is the most frequent etiologic pathogen. Horses are commonly infected, but clinical disease occurs infrequently; the factors influencing disease occurrence are not well understood. Risk factors for the development of EPM include the pre...

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Equine Protozoal Myeloencephalitis: Acupunture Diagnosis

The most accurate method for the diagnosis of equine protozoal myeloencephalitis is the identification of clinical signs and the presence of anti-Sarcocystis neurona antibodies in cerebrospinal fluid; acupuncture is not useful. Author’s addresses: Equine Internal Medicine Consulting, 3288 Valhalla Dr., Lexington, KY 40515 (Fenger) and Dept. of Veterinary Science, 108 Gluck Equine Research Cente...

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Experimental Infection of Horses with Culture-Derived Sarcocystis neurona Merozoites as a Model for Equine Protozoal Myeloencephalitis

A study was designed to develop an experimental model to produce Sarcocystis neurona encephalitis in horses. Sarcocystis neurona, isolated from the spinal cord of an ataxic horse, was placed in continuous culture using bovine turbinate cells, and the cultured S. neurona merozoites were used to infect lymphocytes. A horse that was subsequently experimentally infected with 100,000 of the S. neuro...

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ژورنال

عنوان ژورنال: Journal of Veterinary Diagnostic Investigation

سال: 1993

ISSN: 1040-6387,1943-4936

DOI: 10.1177/104063879300500320